An Epidemiological Retrospective Study of Serum Uric Acid as a Risk Marker in Hypertensive Pregnancies

Authors

  • Sonal Dube Assistant Professor, Department of Obstetrics and Gynaecology, Raipur Institute of Medical Sciences, Raipur, Chhattisgarh, India
  • Neerja Agarwal Professor and Head, Department of Obstetrics and Gynaecology, Raipur Institute of Medical Sciences, Raipur, Chhattisgarh, India

Keywords:

Hypertensive pregnancy, Preeclampsia, Retrospective analysis, Uric acid

Abstract

Introduction: Preeclampsia (PE) may be associated with complications in fetus, such as intrauterine growth restriction, prematurity, and even death of fetus. In women, there may be development of hepatic and renal failure, pulmonary edema, and even stroke. PE may progress to eclampsia. The present study focused on comparing serum uric acid (SUA) levels in normal pregnant and pregnancy-induced hypertension (PIH) women and to correlate SUA levels with severity of PIH.
Methodology: Retrospective Analytical Comparative study of 200 of the randomly selected obstetric patients who seeked care for delivery at the randomly selected obstetrical units was retrospectively identified.
Results: The mean SUA level clearly showed significantly higher levels in case group compared controls. Compared to severity of hypertension SUA levels also tend to increase with increasing severity of PIH. It was clearly observed that maternal and fetal complications during antepartum and postpartum period were higher once SUA >5 mg/dl was taken as a cutoff.
Conclusion: SUA measurement is probably one of the best markers and a useful surrogate for the diagnosis as well as a measure of severity of PE and will be a useful tool for the management of the same.

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Published

2020-11-13

How to Cite

Dube, S., & Agarwal, N. (2020). An Epidemiological Retrospective Study of Serum Uric Acid as a Risk Marker in Hypertensive Pregnancies. Asian Pacific Journal of Health Sciences, 7(4), 81–84. Retrieved from https://www.apjhs.com/index.php/apjhs/article/view/1136