Evaluation of Antiobesity Activity of Bryophyllum pinnatum (Lam) Oken Leaves Extract in Cafeteria Diet Induced Obesity in Rats

Authors

  • Komal Chandra Department of Pharmaceutical Sciences, Sir J C Bose Technical Campus, Bhimtal, Kumaun University, Nainital, Uttarakhand, India
  • Preetam Kumar College of Pharmacy, Graphic Era Hill University, Bhimtal Campus, Nainital, Uttarakhand, India
  • Virender Kaur Department of Pharmaceutical Sciences, Sir J C Bose Technical Campus, Bhimtal, Kumaun University, Nainital, Uttarakhand, India
  • Yatindra Kumar Department of Pharmacy, GSVM Medical College, Kanpur, Uttar Pradesh, India
  • Tirath Kumar Department of Pharmaceutical Sciences, Sir J C Bose Technical Campus, Bhimtal, Kumaun University, Nainital, Uttarakhand, India

DOI:

https://doi.org/10.21276/apjhs.2021.8.3.35

Abstract

Present study was aimed to scrutinize the antiobesity activity of Bryophyllum pinnatum (Lam) Oken leaves aqueous extract (AEBP) in the cafeteria diet-induced obesity in rats. Female Wistar rats weighing between 100-150 g were allocated in five groups (n=6) i.e. normal control, obesity control, standard drug (Orlistat) treated group, test drug (200 mg/kg and 400 mg/kg AEBP) treated groups. The result revealed that B. pinnatum leaves prevented the increase in BMI, food intake, body weight, glucose, triglycerides and cholesterol level without affecting water intake. This study provides evidence for the antiobesity activity of Bryophyllum pinnatum (Lam) Oken leaves.

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Published

2021-07-29

How to Cite

Komal Chandra, Preetam Kumar, Virender Kaur, Yatindra Kumar, & Tirath Kumar. (2021). Evaluation of Antiobesity Activity of Bryophyllum pinnatum (Lam) Oken Leaves Extract in Cafeteria Diet Induced Obesity in Rats. Asian Pacific Journal of Health Sciences, 8(3), 194–200. https://doi.org/10.21276/apjhs.2021.8.3.35