Uropathogenic Escherichia coli Correlation between virulence factors and serotypes

Authors

  • Dr. K. P. Ranjan Department of Microbiology, Gajra Raja Medical College, Gwalior, Madhya Pradesh, India
  • Pooja Tomar Department of Microbiology, Sri Venkateshwara University, Amroha, Uttar Pradesh, India
  • Neelima Ranjan Department of Microbiology, Gajra Raja Medical College, Gwalior, Madhya Pradesh, India
  • Savita B. Jain Department of Microbiology, Gajra Raja Medical College, Gwalior, Madhya Pradesh, India
  • Himanshi Bansal Department of Microbiology, Gajra Raja Medical College, Gwalior, Madhya Pradesh, India

DOI:

https://doi.org/10.21276/apjhs.2018.5.2.1

Keywords:

Biofilm, serotype, urinary tract infections, uropathogenic Escherichia coli, virulence factors

Abstract

Background: Urinary tract infections (UTIs) are the most commonly encountered bacterial infections both in community and
health-care settings. Objective: We determine the prevalence of virulence factors and serotypes associated with uropathogenic
Escherichia coli (UPEC). In addition, we also compare the possible relationship between virulence factors with serotypes.
Materials and Methods: A total of 200 E. coli isolates were collected from clinically suspected UTI and detection of virulence
factors such as hemolysin production, hemagglutination, biofilm formation, and also serotyping was done. Results: The
incidence of UTI was more in the age group of 21–30 years and more in females. Hemolysin production was seen in 23% strains.
Hemagglutination was shown by total 127 (63.5%) isolates. One hundred nine (54.5%) isolates showed production of moderate
and high-value biofilms. Among the serotypes, O1, O2, O8, O90, O101, and O125 were the most commonly isolated uropathogens.
Among all the serotypes of UPEC isolates, maximum hemolysin production and hemagglutination were seen in O8 serotype.
Conclusion: Certain serotypes of UPEC are more commonly associated with UTI. These serotypes have a wide array of virulence
factors and their identification may facilitate the application of more precise approaches in diagnosis of UTIs

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Published

2018-06-30

How to Cite

Dr. K. P. Ranjan, Pooja Tomar, Neelima Ranjan, Savita B. Jain, & Himanshi Bansal. (2018). Uropathogenic Escherichia coli Correlation between virulence factors and serotypes. Asian Pacific Journal of Health Sciences, 5(2), 1–4. https://doi.org/10.21276/apjhs.2018.5.2.1

Issue

Vol. 5 No. 2 (2018): Vol 5 | Issue 2 | April - June 2018

Section

Table of Contents

License

Asian Pacific Journal of Health Sciences applies the Creative Commons Attribution (CC-BY) license to published articles. Under this license, authors retain ownership of the copyright for their content, but they allow anyone to download, reuse, reprint, modify, distribute and/or copy the content as long as the original authors and source are cited. Appropriate attribution can be provided by simply citing the original article.