Carotid intima-media thickness as a predictor of atherosclerosis in diabetic and non-diabetic subjects - A study from tertiary care hospital in coastal city of South India

Authors

  • G. Vikas Naik Kanachur Institute of Medical Sciences, University Road, Natekal, Mangalore - 575 018, Karnataka, India. Phone: +91-9741891158.
  • K. P. Shivaranjan Gleneagles Global Health Centre, Bengaluru, Karnataka, India

DOI:

https://doi.org/10.21276/apjhs.2018.5.1.21

Keywords:

Atherosclerosis, carotid intima-media thickness, ultrasound

Abstract

Background and Objectives: Atherosclerosis typically occurs over a period of many years, usually many decades. After a generally prolonged “silent” period, atherosclerosis may become clinically manifest. Evaluation of intimal medial thickness is considered as surrogate marker of atherosclerosis. B-mode ultrasound was a suitable non-invasive method to visualize the arterial walls and to monitor the early stages of the atherosclerotic process.
Materials and Methods: This is a cross-sectional hospital-based study. A total of 100 patients were selected with 50 patients each in diabetic and non-diabetic groups. After taking consent, patients were subjected for carotid Doppler examination.
Results: The mean intimal medial thickness values of the diabetic subjects (0.12) were significantly higher than those of the non-diabetic (0.07 mm) subjects (P < 0.001). Both in the normal and diabetic subjects, these values increased with age. At any given age, the diabetic subjects had higher values than the non-diabetic subjects. Intimal medial thickness showed a positive correlation with age, gender, hypertension (HTN), hemoglobin A1C, and duration of diabetes with statistically significant P value.
Conclusion: Diabetic subjects have higher intimal medial thickness values than non-diabetic subjects. Diabetes, duration of diabetes, age, gender, and HTN are the most important risk factors associated with increased intimal medial thickness.

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Author Biographies

G. Vikas Naik, Kanachur Institute of Medical Sciences, University Road, Natekal, Mangalore - 575 018, Karnataka, India. Phone: +91-9741891158.

Department of Internal Medicine

K. P. Shivaranjan, Gleneagles Global Health Centre, Bengaluru, Karnataka, India

Department of Gastroenterology

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Published

2018-03-30

How to Cite

G. Vikas Naik, & K. P. Shivaranjan. (2018). Carotid intima-media thickness as a predictor of atherosclerosis in diabetic and non-diabetic subjects - A study from tertiary care hospital in coastal city of South India. Asian Pacific Journal of Health Sciences, 5(1), 100–106. https://doi.org/10.21276/apjhs.2018.5.1.21