Resistance to non-depolarizing neuromuscular blocking agents

Authors

  • Dong-Min Hyun Gangneung Asan Hospital, Gangneung, Gangwon-do, Republic of Korea
  • Young-Mu Kim Gangneung Asan Hospital, Gangneung, Gangwon-do, Republic of Korea
  • Jae-Ho Lee Gangneung Asan Hospital, Gangneung, Gangwon-do, Republic of Korea
  • Jin Sun Kim Gangneung, Gangwon-do, Republic of Korea
  • Hong Seuk Yang Daejeon Sun Hospital, Daejeon, Republic of Korea

DOI:

https://doi.org/10.21276/apjhs.2020.7.1.14

Keywords:

Non-depolaring neuromuscular blocking agents, Resistance, Rocuronium

Abstract

The authors experienced three cases of the resistance to the nondepolarizing neuromuscular blocking agents (NMBAs), rocuronium. There are many factors that affect NMBAs such as steroid, endocrine or autoimmune diseases which are thyroid disease, parathyroid disease, myasthenia gravis and etc., and anticonvulsant medication. However, in these three cases, the patients did not have any neuromuscular disorder, except certain drug administration, smoking, endocrine disorder and fever. In this study, we report three cases of the resistance to rocuronium where the resistance duration was much shorter than known and we should be aware of the importance of neuromuscular monitoring.

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Author Biographies

Dong-Min Hyun, Gangneung Asan Hospital, Gangneung, Gangwon-do, Republic of Korea

Department of Anesthesiology and Pain Medicine,

Young-Mu Kim, Gangneung Asan Hospital, Gangneung, Gangwon-do, Republic of Korea

Department of Anesthesiology and Pain Medicine, 

Jae-Ho Lee, Gangneung Asan Hospital, Gangneung, Gangwon-do, Republic of Korea

Department of Anesthesiology and Pain Medicine, 

Jin Sun Kim, Gangneung, Gangwon-do, Republic of Korea

Department of Anesthesiology and Pain Medicine, Gangneung Asan Hospital, 

Hong Seuk Yang, Daejeon Sun Hospital, Daejeon, Republic of Korea

Department of Anesthesiology and Pain Medicine,

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Published

2020-03-30

How to Cite

Dong-Min Hyun, Young-Mu Kim, Jae-Ho Lee, Jin Sun Kim, & Hong Seuk Yang. (2020). Resistance to non-depolarizing neuromuscular blocking agents. Asian Pacific Journal of Health Sciences, 7(1), 74–80. https://doi.org/10.21276/apjhs.2020.7.1.14