Understanding the Pharmacodynamics of Kriyakalpa

Abstract

Pharmacodynamics is the study of a drug’s molecular, biochemical, and physiologic effects. In short, it is all about how a drug affects an organism. There are some important factors that play an important role in the absorption of drugs in the body, like the route of drug administration, solubility and bioavailability, physical state of the drug and molecular weight, Time of absorption, and Vascularity of the absorbing surface. In Ayurveda, the local treatment procedures of Netra are explained in the name of Netra Kriya Kalpa (Su. U. 18/2). The word kriya means therapeutic action, and kalpana means specific formulations. Kriya Kalpa is a Bahirparimarjana Chikitsa and has several advantages over oral administration. They are noninvasive and cost-effective. No biodegradation of Drugs, Effective against blood aqueous and blood-retinal barriers, Comparatively, less dose is required, and it can be used as a preventive as well as a curative. Overall, we can say that Kriyakalp Procedures have several advantages as compared to oral administration.