Role of Kataka-Khadiradi Ghanavati Ayurvedic Formulation in the Management of Diabetic Retinopathy

Abstract

Introduction: Metabolic disorders are considerable health issues due to their association with morbidities and mortalities. Diabetes is one of the metabolic disorders associated with every systemic morbidity. Diabetic retinopathy (DR) is one of such morbidity which is vision-threatening and the whole world is looking for a solution. In contemporary science, there are management techniques which are applicable when DR is completely manifested. Objectives: The objective of this study was to review existing pharmaco-analytical reports on Katakakhadiradi Kashaya (KKK) and Ghanavati and its contents, animal studies and clinical trials of management of diabetes, and its complications through the KKK and Ghanavati (KKG). Design: The literature research comprised an electronic database from January 2000 to February 4, 2023. The study included MEDLINE, PubMed, the Cochrane Library, Google Scholar, AYUSH Research Portal, and DHARA database. Search terms were used “KKK”, “DR”, “Katakakhadiradi Ghanavati”, and “Antioxidants.” No limits were used. The search strategy was adapted for each database as necessary. Pharmaco-analytical reports and animal studies were included in the current review. The study applied inclusion criteria while screening the records. Intervention: Phytochemical constituents and their effect on DR. Outcome measures: Number and results of studies identified in the review. Results: The integrative approach could open new hope for patients of DR and is a need of time.